Click Here to return To Results

 

Regress of HIV Enceph & Basal Ganglia Signal Intensity Abnor MRI in AIDS after Protease Inhibitor Neuroradiology 206:491-498, Filippi,C.G.,et al, 1998 See this aricle in Pubmed Article Abstract Of the nine patients receiving protease inhibitors,four showed nearly complete regression,four showed interval stability,and one showed slight progression.Thus,eight patients(89%)demonstrated either stability or improvement in white matter disease,which correlated with cognitive improvement.Of the seven patients not receiving protease inhibitors,six (86%)showed marked progression with a decline in cognitive function and one had no interval change.The difference between the two groups was statistically significant.Of the two patients receiving protease inhibitors who initially had basal ganglia signal intensity abnormalities, one demonstrated resolution and one nearly complete resolution subsequently.Although the patient population is small,protease inhibitors may cause regression of periventricular white matter and basal ganglia signal intensity abnormalities in HIV encephalopathy and may have a role in treatment.

Related Tags

(click to filter results - removes previous filter) acquired immunodeficiency syndrome acquired immunodeficiency syndrome dementia complex basal ganglia basal ganglia,lesion of CD4 counts encephalitis,human immunodeficiency virus type 1 encephalopathy human immunodeficiency virus type 1 MRI MRI,abnormal MRI,disappearing lesion on MRI,high signal intensity of basal ganglia MRI,serial protease inhibitor,HIV-1 treatment of neurologic disorder white matter disease

Click Here to return To Results